Gonzalez Cardona, J., Smith, M. D., Wang, J., Kirby, L., Schott, J. T., Davidson, T., … Calabresi, P. A. (2019). Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis. PLOS ONE14(9), e0221747. https://doi.org/10.1371/journal.pone.0221747

Kirby, L., Jin, J., Cardona, J. G., Smith, M. D., Martin, K. A., Wang, J., … Calabresi, P. A. (2019). Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination. Nature Communications10(1), 3887. https://doi.org/10.1038/s41467-019-11638-3

Hollinger, K. R., Smith, M. D., Kirby, L. A., Prchalova, E., Alt, J., Rais, R., … Calabresi, P. A., Slusher, B. S. (2019). Glutamine antagonism attenuates physical and cognitive deficits in a model of MS. Neurology - Neuroimmunology Neuroinflammation6(6), e609. https://doi.org/10.1212/NXI.0000000000000609

Jin, J., Smith, M. D., Kersbergen, C. J., Kam, T.-I., Viswanathan, M., Martin, K., … Calabresi, P. A. (2019). Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis. Acta Neuropathologica Communications, 7(1), 125. https://doi.org/10.1186/s40478-019-0767-6

Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, … Calabresi, P.A. (2019) Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain. doi:10.1093/brain/awz188

Bhargava, P., Mische, L., Smith, M. D., Harrington, E., Fitzgerald, K. C., Martin, K., … Calabresi, P. A. (2019). Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation. BioRxiv, 627356. https://doi.org/10.1101/627356

Bhargava, P., Wicken, C., Smith, M. D., Strowd, R. E., Cortese, I., Reich, D. S., … Calabresi, P. A., Mowry, E. M. (2019). Trial of intrathecal rituximab in progressive multiple sclerosis patients with evidence of leptomeningeal contrast enhancement. Multiple Sclerosis and Related Disorders, 30, 136–140. https://doi.org/10.1016/j.msard.2019.02.013

Horti, A. G., Naik, R., Foss, C. A., Minn, I., Misheneva, V., Du, Y., … Calabresi, P. A., … Pomper, M. G. (2019). PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R). Proceedings of the National Academy of Sciences of the United States of America, 201812155. https://doi.org/10.1073/pnas.1812155116

Bhargava, P., Fitzgerald, K. C., Venkata, S. L. V., Smith, M. D., Kornberg, M. D., Mowry, E. M., … Calabresi, P. A. (2018). Dimethyl fumarate treatment induces lipid metabolism alterations that are linked to immunological changes. Annals of Clinical and Translational Neurology. https://doi.org/10.1002/acn3.676

Kornberg, M. D., Bhargava, P., Kim, P. M., Putluri, V., Snowman, A. M., Putluri, N., Calabresi, P. A., Snyder, S. H. (2018). Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity. Science. https://doi.org/10.1126/science.aan4665

Kornberg, M. D., Smith, M. D., Shirazi, H. A., Calabresi, P. A., Snyder, S. H., & Kim, P. M. (2018). Bryostatin-1 alleviates experimental multiple sclerosis. Proceedings of the National Academy of Sciences, 201719902. https://doi.org/10.1073/pnas.1719902115

Calabresi, P. A. (2018). Advances in multiple sclerosis: from reduced relapses to remedies. The Lancet Neurology, 17(1), 10–12. http://doi.org/10.1016/S1474-4422(17)30417-9

Reich, D. S., Lucchinetti, C. F., & Calabresi, P. A. (2018). Multiple Sclerosis. New England Journal of Medicine, 378(2), 169–180. http://doi.org/10.1056/NEJMra1401483

Smith, M. D., Calabresi, P. A., & Bhargava, P. (2017). Dimethyl fumarate treatment alters NK cell function in multiple sclerosis. European Journal of Immunology. http://doi.org/10.1002/eji.201747277

Baxi, E. G., DeBruin, J., Jin, J., Strasburger, H. J., Smith, M. D., Orthmann-Murphy, J. L., … Calabresi, P. A. (2017). Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination. Glia. http://doi.org/10.1002/glia.23229

Smith, M. D., Martin, K. A., Calabresi, P. A., & Bhargava, P. (2017). Dimethyl fumarate alters B-cell memory and cytokine production in MS patients. Annals of Clinical and Translational Neurology, 4(5), 351–355. http://doi.org/10.1002/acn3.411

Glenn, J. D., Smith, M. D., Xue, P., Chan-Li, Y., Collins, S., Calabresi, P. A., … Whartenby, K. A. (2017). CNS-targeted autoimmunity leads to increased influenza mortality in mice. The Journal of Experimental Medicine, 214(2), jem.20160517. http://doi.org/10.1084/jem.20160517

Orthmann-Murphy, J. L., & Calabresi, P. A. (2017). Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis. Clinical Pharmacology and Therapeutics, 101(1), 52–64. http://doi.org/10.1002/cpt.547

Schott, J. T., Kirby, L. A., Calabresi, P. A., & Baxi, E. G. (2016). Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning. Journal of Visualized Experiments, (108), 53764. http://doi.org/10.3791/53764

Bhargava, P., & Calabresi, P. A. (2016). Metabolomics in multiple sclerosis. Multiple Sclerosis Journal, 22(4), 451–460. http://doi.org/10.1177/1352458515622827

Sotirchos, E. S., Bhargava, P., Eckstein, C., Van Haren, K., Baynes, M., Ntranos, A., … Calabresi, P. A. (2016). Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. Neurology, 86(4), 382–390. http://doi.org/10.1212/WNL.000000000000231

Grishkan, I. V, Tosi, D. M., Bowman, M. D., Harary, M., Calabresi, P. A., & Gocke, A. R. (2015). Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3-Independent T Cells with Suppressive Properties. Journal of Immunology (Baltimore, Md. : 1950). http://doi.org/10.4049/jimmunol.1403024

Baxi, E. G., DeBruin, J., Tosi, D. M., Grishkan, I. V., Smith, M. D., Kirby, L. A., … Gocke, A. R. (2015). Transfer of Myelin-Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone-Fed Mice. Journal of Neuroscience, 35(22), 8626–8639. http://doi.org/10.1523/JNEUROSCI.3817-14.2015

Bhargava, P., Gocke, A., & Calabresi, P. A. (2015). 1,25-Dihydroxyvitamin D3 impairs the differentiation of effector memory T cells in vitro in multiple sclerosis patients and healthy controls. Journal of Neuroimmunology, 279, 20–4. http://doi.org/10.1016/j.jneuroim.2014.12.018

Baxi, E. G., Schott, J. T., Fairchild, A. N., Kirby, L. A., Karani, R., Uapinyoying, P., … Calabresi, P. A. (2014). A selective thyroid hormone β receptor agonist enhances human and rodent oligodendrocyte differentiation. Glia, 62(9), 1513–29. http://doi.org/10.1002/glia.22697

Ntranos, A., Hall, O., Robinson, D. P., Grishkan, I. V, Schott, J. T., Tosi, D. M., … Gocke, A. R. (2014). FTY720 impairs CD8 T-cell function independently of the sphingosine-1-phosphate pathway. Journal of Neuroimmunology, 270(1–2), 13–21. http://doi.org/10.1016/j.jneuroim.2014.03.007

Grishkan, I. V, Fairchild, A. N., Calabresi, P. A., & Gocke, A. R. (2013). 1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization. Proceedings of the National Academy of Sciences of the United States of America, 110(52), 21101–6. http://doi.org/10.1073/pnas.1306072110

Grishkan, I. V, Ntranos, A., Calabresi, P. A., & Gocke, A. R. Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells. Cellular Immunology, 284(1–2), 68–74. http://doi.org/10.1016/j.cellimm.2013.06.011

Hu, L., Wang, T., Gocke, A. R., Nath, A., Zhang, H., Margolick, J. B., … Calabresi, P. A. (2013). Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes. PloS One, 8(1), e54267. http://doi.org/10.1371/journal.pone.0054267

Gocke, A. R., Lebson, L. A., Grishkan, I. V, Hu, L., Nguyen, H. M., Whartenby, K. A., … Calabresi, P. A. (2012). Kv1.3 deletion biases T cells toward an immunoregulatory phenotype and renders mice resistant to autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950), 188(12), 5877–86. http://doi.org/10.4049/jimmunol.1103095

Hu, L., Gocke, A. R., Knapp, E., Rosenzweig, J. M., Grishkan, I. V, Baxi, E. G., … Calabresi, P. A. (2012). Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21cip1 signaling. The Journal of Biological Chemistry, 287(2), 1261–8. http://doi.org/10.1074/jbc.M111.296798